Nesrine Amdouni1, Ikram Chamtouri1, Asma Ben Abdallah1, Walid Jomaa1, Khaldoun Ben Hamda1, Faouzi Maatouk1

1CHU FAttouma Bourguiba Monastir, Monastir, Tunisia

Background:
Coronary disease represent a major cause of morbidity and mortality worldwide. In this study, we aimed to determine biological factors predicting in hospital death following primary percutaneous coronary intervention (PCI) for ST elevation myocardial infarction (STEMI).

Method(s):
We reviewed data from retrospective registry including 352 patients admitted in  cardiology B department of Fattouma Bourguiba University Hospital from January 2000 to March 2017 for STEMI. All patients were managed by primary PCI.

Result(s):
In hospital mortality rate was 11.9% in the overall population. It was higher in women (23.2% vs 9.8% ; p=0.005). Its biological predicting factors in univariate analysis were : anaemia (p=0.006), particulary severe anemia with haemoglobin level below 8g/dl (p<0.001), renal failure (p<0.001), hyperglycemia (blood glucose level greater than 11mmol/l) (p<0.001), leucocytosis (white blood cells count over 14.000/mm³) (p=0.005) and platelet count over 250.000/mm³ (p=0.037). In multivariate analysis, only renal failure and anemia were independent predincting factors of in hospital mortality (p<0.001).

Conclusion(s):
In hospital mortality following STEMI remain high in the developing countries. Recognizing and understanding the biological risk factors of mortality after STEMI provide clinicians important information to determine prognosis.