Ikram Chamtouri, Nesrine Amdouni1, Wajih Abdallah1, Waldi Jomaa1, Khaldoun Ben Hamda1, Faouzimaatouk1

1Fattouma Bourguiba University Hospital, Monastir, Tunisia

The influence of sex on the prevalence of valvular heart diseases is already known. But we have little information about the differences between women and men in infective endocarditis (IE) characteristics.

The aim of this study is to study the clinical characteristics and prognostic features of IE in women compared to those in men.

This is a mono-centric retrospective study including 245 patients in cardiology B department of Fattouma Bourguiba University Hospital, Monastir, Tunisia from January 2000 and to December 2019. All patients with IE were included. IE diagnosis was established according to Duke’s criteria.

In our study, 106 patients were female (43.3%). The mean age was similar in both sexes (36 ± 18.6 years for women vs. 38.45 ± 17.2 years for men; p = 0.2). For left heart IE, mitral involvement was significantly higher in women (35.8% vs. 25.9%; p = 0.042). The right heart involvement was similar in both sexes (9.5% in women vs. 7.2% in men; p = 0.13). The occurrence of IE on prosthetic valves was significantly lower in women (19.4% vs. 29.5%; p = 0.047). Analysis of the two groups did not show a significant difference in the incidence of peripheral embolism (23.6% in women vs. 16.5% in men; p = 0.11) and in-hospital mortality (19% in women vs 18.7% in men; p = 0.53). The indication for surgery was similar in both groups (33% in women vs. 29.5% in men; p = 0.23).

this descriptive study concluded that there is a difference in the location of IE according to sex without resulting in any particular clinical or prognostic consequences