Ghufran Adnan1, Intisar Ahmed1, Javed Majid Tai1, Maria Ali Khan1

1Aga Khan University, Karachi, Pakistan

Background:
Revascularization of the saphenous vein grafts is challenging and debated for the last few decades. Percutaneous revascularization of saphenous vein grafts is reported to have poor long-term outcomes than native coronary artery revascularization. We aim to study the peri-procedural complications and long-term outcomes of percutaneous revascularization of saphenous vein grafts in a low-middle-income country.

Method(s):
In this retrospective study, we included 110 patients who underwent percutaneous revascularization from January 2011 to March 2020 and followed them retrospectively for long term outcomes and major adverse cardiovascular events

Result(s):
The mean age of our study population was 71 ±9 years,  81% were male and the mean follow-up period of the study was 48±27 months. The most common reason for the presentation was non-ST elevation myocardial infarction (46%) and hypertension was the most common associated comorbid condition (86%). Drug-eluting stent (80%) was placed in most of the patients, followed by BMS (14%) and POBA (6%) and we did not find a statistically significant difference in major adverse cardiovascular events (P=0.48), target vessel revascularization (p=0.69), and target lesion revascularization (p=0.54) among these groups. The mean period from CABG to SVG PCI was 15± 5.5 years. Multivariate Cox regression analysis showed that acute coronary syndrome, stroke, and female gender were independently associated with major adverse cardiovascular events…

Conclusion(s):
Long term outcomes of saphenous vein graft PCI are not affected by the type of stents. Female gender, acute coronary syndrome, and stroke are the independent predictors of major adverse cardiovascular events and statin therapy has a positive impact on long term outcomes of saphenous vein graft PCI